If Promethazine with Codeine Oral Remedy is used for a prolonged time period in a very Expecting female, recommend the affected individual of the potential risk of neonatal opioid withdrawal syndrome and make sure acceptable procedure will be accessible [see Warnings and Safeguards (5.20)].

Promethazine with Codeine Oral Solution is indicated with the temporary relief of coughs and upper respiratory indicators related to allergy or maybe the popular chilly in patients eighteen a long time of age and more mature.

Promethazine may perhaps result in other side effects. Call your health practitioner if you practical experience any uncommon challenges when you are taking this medication.

Codeine and hydrocodone are opioid soreness aid drugs that Health professionals prescribe to take care of soreness in certain circumstances. Hydrocodone is stronger than codeine and comes with a heightened prospective for addiction.

The diagnostic evaluation of individuals with this syndrome is intricate. In arriving at a prognosis, it is necessary to establish circumstances where by the scientific presentation incorporates both equally critical health care sickness (e.

Before using this medication, tell your physician or pharmacist if you are allergic to promethazine or to dextromethorphan; or to any other phenothiazines (which include prochlorperazine); or Should you have almost every other allergies.

Mainly because these reactions could possibly be reported voluntarily from a inhabitants of unsure dimensions, It's not necessarily always achievable to reliably estimate their frequency or create a causal relationship to drug exposure.

Assess Each individual affected person's danger before prescribing Promethazine with Codeine Oral Alternative, prescribe Promethazine with Codeine Promethazine codeine syrup Oral Remedy for the shortest duration that is certainly consistent with particular person affected individual cure objectives, watch all sufferers regularly for the development of addition or abuse, and refill only after reevaluation of the need for ongoing treatment method. [see Warnings and Safeguards (five.one)]

It is highly recommended to keep any products and solutions with hydrocodone locked up and outside of get to of youngsters. Even 1 dose of hydrocodone can lead to a fatal overdose in small children

Codeine is absorbed through the gastrointestinal tract with most plasma focus developing 60 minutes article administration. The presence of a high-Body fat, substantial-calorie meal didn't drastically impression the PK of codeine.

Reevaluate individuals with unresponsive cough in five days or faster for attainable fundamental pathology, including overseas system or lessen respiratory tract ailment.

Abdomen or bowel blockage (which include paralytic ileus)—Shouldn't be Employed in individuals Using these conditions.

Utilization of cytochrome P450 3A4 inducers, 3A4 inhibitors, or 2D6 inhibitors with Promethazine with Codeine Oral Remedy needs thorough consideration of the effects over the parent drug, codeine, plus the Energetic metabolite, morphine.

The subsequent really serious adverse reactions are explained, or described in bigger detail, in other sections: